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Etymologie

Was (wer) ist hyperkeratosis congenita - definition

THICKENING OF THE STRATUM CORNEUM (THE OUTERMOST LAYER OF THE EPIDERMIS), OFTEN ASSOCIATED WITH THE PRESENCE OF AN ABNORMAL QUANTITY OF KERATIN

Plantar hyperkeratosis; Hyperkeratoses; Hyperkeratosis of the nipple and areola; Hyperkeratosis lenticularis perstans; Flegel's disease; Flegel disease; Hyperkeratosis lenticularis perstans of Flegel; Follicular hyperkeratosis; Follicular Hyperkeratosis; Hyperkeratotic; Hypokeratosis

Pachyonychia congenita

RARE GROUP OF AUTOSOMAL DOMINANT SKIN DISORDERS THAT ARE CAUSED BY A MUTATION IN ONE OF FIVE DIFFERENT KERATIN GENES

Pachyonychia; Pachyonychia congenita type I; Pachyonychia congenital type I; Jadassohn-Lewandown-Sky syndrome; Pachyonychia congenita type II; Jackson-Lawler pachyonychia congenita; Jackson-Sertoli syndrome; Jackson-Lawler type pachyonychia congenita; Jadassohn–Lewandowsky syndrome; Jackson–Lawler pachyonychia congenita; Jackson–Sertoli syndrome; Jadassohn-Lewandowsky syndrome; Pachyonychia congenita type III; Schafer-Brunauer syndrome; Jackson-Lawler syndrome; Jadasssohn-Lewandowsky syndrome; Jadassohn Lewandowsky syndrome; Pachyonychia congenita Jackson Lawler type; Pachyonychia congenita Jackson–Lawler type; Pachyonychia congenita Jackson-Lawler type; Pachyonychia congenita type 1; Pachyonychia congenita type 2

Pachyonychia congenita (often abbreviated as "PC") is a rare group of autosomal dominant skin disorders that are caused by a mutation in one of five different keratin genes. Pachyonychia congenita is often associated with thickened toenails, plantar keratoderma, and plantar pain.

https://en.wikipedia.org/wiki/Pachyonychia_congenita

hyperkeratosis

[?h??p?k?r?'t??s?s]

¦ noun Medicine abnormal thickening of the outer layer of the skin.

Multiple minute digitate hyperkeratosis

MEDICAL CONDITION

Digitate keratoses; Disseminated spiked hyperkeratosis; Familial disseminated piliform hyperkeratosis; Minute aggregate keratosis; Digitate keratosis

Multiple minute digitate hyperkeratosis (also known as "Digitate keratoses," "Disseminated spiked hyperkeratosis," "Familial disseminated piliform hyperkeratosis," and "Minute aggregate keratosis") is a rare cutaneous condition, with about half of cases being familial, inherited in an autosomal dominant fashion, while the other half are sporadic.

https://en.wikipedia.org/wiki/Multiple_minute_digitate_hyperkeratosis

Wikipedia

Hyperkeratosis

Hyperkeratosis is thickening of the stratum corneum (the outermost layer of the epidermis, or skin), often associated with the presence of an abnormal quantity of keratin, and also usually accompanied by an increase in the granular layer. As the corneum layer normally varies greatly in thickness in different sites, some experience is needed to assess minor degrees of hyperkeratosis.

It can be caused by vitamin A deficiency or chronic exposure to arsenic.

Hyperkeratosis can also be caused by B-Raf inhibitor drugs such as Vemurafenib and Dabrafenib.

It can be treated with urea-containing creams, which dissolve the intercellular matrix of the cells of the stratum corneum, promoting desquamation of scaly skin, eventually resulting in softening of hyperkeratotic areas.

https://en.wikipedia.org/wiki/Hyperkeratosis